three discovery plays
1Discovery Ensemble — Also known as DE Origin Boston, Massachusetts, USA Genres Classical Occupations Chamber orchestra Years active 2008–pr …
2Discovery and development of angiotensin receptor blockers — The angiotensin receptor blockers (ARBs), also called angiotensin (AT1) receptor antagonists or sartans, are a group of anti hypertensive drugs that act by blocking the effects of the hormone angiotensin II (Ang II) in the body, thereby lowering… …
3Discovery and development of renin inhibitors — Renin inhibitors are antihypertensive drugs that inhibit the first and rate limiting step of the renin angiotensin aldosterone system (RAAS). Since the 1970s scientists have been trying to develop potent inhibitors with acceptable oral… …
4Discovery and development of cyclooxygenase 2 inhibitors — Cyclooxygenases are enzymes that take part in a complex biosynthetic cascade that results in the conversion of polyunsaturated fatty acids to prostaglandins and thromboxane(s).[1] Their main role is to catalyze the transformation of arachidonic… …
5Discovery and development of antiandrogens — In the 1960s, the first antiandrogen, or androgen antagonist, was discovered. Antiandrogens antagonise the androgen receptor (AR) and thereby block the biological effects of testosterone and dihydrotestosterone (DHT). Antiandrogens are important… …
6Discovery and development of cephalosporins — Cephalosporins are a broad class of bactericidal antibiotics that include the β lactam ring and share a structural similarity and mechanism of action with other β lactam antibiotics (e.g. penicillins, carbapenems and aztreonam).[1] The… …
7Discovery and development of tubulin inhibitors — Tubulin inhibitors interfere directly with the tubulin system which is in contrast to those drugs acting on DNA for cancer chemotherapy. Microtubules play an important role in eukaryotic cells. Alpha and beta tubulin, the main components of… …
8Discovery (observation) — Sightings redirects here. For other uses, see Sightings (disambiguation). A personification of discovery as represented by a statue in The American Adventure in the World Showcase pavilion of Walt Disney World s Epcot. Discovery is the act of… …
9Discovery and development of small molecule c-Met inhibitors — The c Met (mesenchymal epithelial transition) tyrosine kinase stimulates cell scattering, invasion, protection from apoptosis and angiogenesis.[1] c Met is a receptor tyrosine kinase,[2] which can cause a wide variety of different cancers, such… …
10Three Kings Islands — The Three Kings Islands ( Manawa tawhi or Ngā Motu Karaka in Māori) are a group of 13 islands about 55 kilometres (35 miles) northwest of Cape Reinga, the northernmost point of the North Island of New Zealand, where the South Pacific Ocean and… …
