self-tissue antigen
1antigen — Any substance that, as a result of coming in contact with appropriate cells, induces a state of sensitivity and/or immune responsiveness after a latent period (days to weeks) and that reacts in a demonstrable way with antibodies and/or immune… …
2Human leukocyte antigen — The human leukocyte antigen system (HLA) is the name of the major histocompatibility complex (MHC) in humans. The superlocus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6 …
3major histocompatibility antigen — A cell surface protein or glycoprotein that allows the immune system to distinguish foreign or non self from self . A better term is histoglobulin. These are the antigens that must be matched between donors and recipients during organ and tissue… …
4immune system disorder — Introduction Disorders of the immune systemany of various failures in the body s defense mechanisms against infectious organisms (see table (Disorders of the immune system)). Disorders of immunity include immune deficiency diseases, such… …
5Molecular mimicry — is defined as the theoretical possibility that sequence similarities between foreign and self peptides are sufficient to result in the cross activation of autoreactive T or B cells by pathogen derived peptides. Despite the promiscuity of several… …
6Clonal selection — of lymphocytes: 1) A hematopoietic stem cell undergoes differentiation and genetic rearrangement to produce 2) immature lymphocytes with many different antigen receptors. Those that bind to 3) antigens from the body s own tissues are destroyed,… …
7Cytotoxic T cell — Antigen presentation stimulates T cells to become either cytotoxic CD8+ cells or helper CD4+ cells. A cytotoxic T cell (also known as TC, Cytotoxic T Lymphocyte, CTL, T Killer cell, cytolytic T cell, CD8+ T cells or killer T cell) belongs to a… …
8immune system — Anat. a diffuse, complex network of interacting cells, cell products, and cell forming tissues that protects the body from pathogens and other foreign substances, destroys infected and malignant cells, and removes cellular debris: the system… …
9human disease — Introduction an impairment of the normal state of a human being that interrupts or modifies its vital functions. health versus disease Before human disease can be discussed, the meanings of the terms health, physical fitness, illness …
10Immune system — A scanning electron microscope image of a single neutrophil (yellow), engulfing anthrax bacteria (orange). An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and… …
