receptor-binding screening
1receptor-binding screening — A biotechnology based method for drug discovery, which relies on the fact that many drugs act by binding to specific receptors on or in cells. Since receptors in vivo bind to hormones or to other cells, and thereby control the cell s behaviour, a …
2Peroxisome proliferator-activated receptor gamma — PDB rendering based on 1fm6 …
3Discovery and development of angiotensin receptor blockers — The angiotensin receptor blockers (ARBs), also called angiotensin (AT1) receptor antagonists or sartans, are a group of anti hypertensive drugs that act by blocking the effects of the hormone angiotensin II (Ang II) in the body, thereby lowering… …
4Dopamine receptor D2 — Rendering based on PDB 1I15 …
5Phosphatidylethanolamine binding protein 1 — PDB rendering based on 1a44 …
6CCR5 receptor antagonists — are a class of small molecules that antagonize the CCR5 receptor. The C C motif chemokine receptor CCR5 is involved in the HIV entry process. Hence antagonists of this receptor have potential therapeutic applications in the treatment of HIV… …
7NK1 receptor antagonist — Neurokinin 1 (NK1) antagonists are a novel class of medications that possesses unique antidepressant,[1] anxiolytic,[2] and antiemetic properties. The discovery of neurokinin 1 (NK1) receptor antagonists was a turning point in the prevention of… …
8Two-hybrid screening — Overview of two hybrid assay, checking for interactions between two proteins, called here Bait and Prey . A. Gal4 transcription factor gene produces two domain protein ( BD and AD ) which is essential for transcription of the reporter gene ( LacZ …
9Metabotropic glutamate receptor 4 — Glutamate receptor, metabotropic 4 Identifiers Symbols GRM4; GPRC1D; MGC177594; MGLUR4; mGlu4 External IDs …
10Orphan receptor — An orphan receptor is an apparent receptor that has a similar structure to other identified receptors but whose endogenous ligand has not yet been identified. If a ligand for an orphan receptor is later discovered, the receptor is referred to as… …
