radioligand assay

  • 1radioligand assay — any assay procedure that uses radioisotopic labeling and biologically specific binding of reagents, such as a radioimmunoassay, competitive protein binding assay, or radioreceptor assay …

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  • 2Radioligand — A radioligand is a radioactive biochemical substance (in particular, a ligand) that is used for diagnosis or for research oriented study of the receptor systems of the body.In a neuroimaging application the radioligand is injected into the… …

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  • 3radioreceptor assay — ra·dio·re·cep·tor assay ri sep tər n an assay for a substance and esp. a hormone in which a mixture of the test sample and a known amount of the radiolabeled substance under test is exposed to a measured quantity of receptors for the substance… …

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  • 4IC50 — The IC50 is a measure of the effectiveness of a compound in inhibiting biological or biochemical function. Often, the compound in question is a drug candidate. This quantitative measure indicates how much of a particular drug or other substance… …

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  • 5CI50 — La concentration inhibitrice à 50% ou CI50 (IC50 en anglais pour Inhibitory Concentration 50) est une mesure de l efficacité d un composé donné pour inhiber une fonction biologique ou biochimique spécifique. Souvent, le composé en question est un …

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  • 6Schild regression — analysis, named for Heinz Otto Schild, is a useful tool for studying the effects of agonists and antagonists on the cellular response caused by the receptor or on ligand receptor binding. Using a dose response curve or an equivalent curve with… …

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  • 7radioreceptor — 1. A receptor that normally responds to radiant energy such as light or heat. 2. A receptor used as a binding agent for unlabeled and radiolabeled analyte in a type of competitive binding assay called r …

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  • 8Clinical Neurochemistry — Progression of Huntington s Diesase. A microscope image of Medium spiny neurons (yellow) with nuclear inclusions (orange), which occur as part of the disease process. Clinical Neurochemistry is the field of neurological biochemistry which relates …

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  • 9Radioactivity in biological research — Radioactivity can be used in life sciences as a radiolabel to easily visualise components or target molecules in a biological system. Radionuclei are synthesised in particle accelerators and have short half lives, giving them high maximum… …

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  • 10Ketanserin — drugbox IUPAC name = 3 [2 [4 (4 fluorobenzoyl)piperidin 1 yl] ethyl] 1 H quinazoline 2,4 dione CAS number = 74050 98 9 ATC prefix = C02 ATC suffix = KD01 PubChem = 3822 DrugBank = chemical formula = C=22|H22|F=1|N=3|O=3 molecular weight = 395.43… …

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