origin of replication
41Licensing factor — A Licensing Factor is a protein or complex of proteins that allows an origin of replication to begin DNA replication at that site. They are thought to primarily occur in Eukaryotic cells, since Prokaryotes use simpler systems to initiate… …
42Chromosome combing — (also known as molecular combing or DNA combing) is a technique used to produce an array of uniformly stretched DNA that is then highly suitable for nucleic acid hybridization studies such as fluorescent in situ hybridisation (FISH) which benefit …
43Cell division cycle 7-related protein kinase — Cell division cycle 7 homolog (S. cerevisiae), also known as CDC7, is a human gene.cite web | title = Entrez Gene: CDC7 cell division cycle 7 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …
44Chromosome — For a non technical introduction to the topic, see Introduction to genetics. Diagram of a replicated and condensed metaphase eukaryotic chromosome. (1) Chromatid – one of the two identical parts of the chromosome after S phase. (2)… …
45Primer (molecular biology) — A primer is a strand of nucleic acid that serves as a starting point for DNA synthesis. They are required for DNA replication because the enzymes that catalyze this process, DNA polymerases, can only add new nucleotides to an existing strand of… …
46Topoisomerase — Topoisomerases (type I: EC 5.99.1.2, type II: EC 5.99.1.3) are enzymes that regulate the overwinding or underwinding of DNA. The winding problem of DNA arises due to the intertwined nature of its double helical structure. For example, during DNA… …
47DNA polymerase — 3D structure of the DNA binding helix turn helix motifs in human DNA polymerase beta A DNA polymerase is an enzyme that helps catalyze in the polymerization of deoxyribonucleotides into a DNA strand. DNA polymerases are best known for their… …
48Primase — DNA primase is an enzyme involved in the replication of DNA. Primase catalyzes the synthesis of a short RNA (or DNA in some organisms [1]) segment called a primer complementary to a ssDNA template. Primase is of key importance in DNA replication… …
49DNA polymerase I — Functional domains in the Klenow Fragment (left) and DNA Polymerase I (right). DNA Polymerase I (or Pol I) is an enzyme that participates in the process of DNA replication in prokaryotes. It is composed of 928 amino acids, and is an example of a… …
50DNA clamp — Top and side views of a homotrimer of the human PCNA sliding clamp (rainbow colored, N terminus = blue, C term …
