oligonucleotide probe

  • 61Nucleic acid thermodynamics — is the study of the thermodynamics of nucleic acid molecules, or how temperature affects nucleic acid structure. For multiple copies of DNA molecules, the melting temperature (Tm) is defined as the temperature at which half of the DNA strands are …

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  • 62TaqMan — ] . The TaqMan Real time PCR measures accumulation of a product via the fluorophore during the exponential stages of the PCR, rather than at the end point as in conventional PCR. The exponential increase of the product is used to determine the… …

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  • 63ChIP-on-chip — Workflow overview of a ChIP on chip experiment. Contents …

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  • 64Microarray analysis techniques — Example of an approximately 40,000 probe spotted oligo microarray with enlarged inset to show detail. Microarray analysis techniques are used in interpreting the data generated from experiments on DNA, RNA, and protein microarrays, which allow… …

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  • 65Tiling array — Tiling Arrays are a subtype of microarray chips. They function on a similar principle to traditional microarrays in that labeled target molecules are hybridized to unlabeled probes fixed on to a solid surface. Tiling arrays differ in the nature… …

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  • 66Massive parallel sequencing — is a term used to describe several revolutionary approaches to DNA sequencing, the so called next generation sequencing (NGS) technologies or second generation sequencing. These sequencing technologies have emerged in late 1996 [1][2] an have… …

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  • 67ABI Solid Sequencing — is a form of DNA sequencing. DNA sequencing encompasses biochemical methods for determining the order of the nucleotide bases, adenine, guanine, cytosine, 5 methyl cytosine, and thymine, in a DNA oligonucleotide which is described by McKernan,… …

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  • 68DNA denaturation — DNA denaturation, also called DNA melting, is the process by which double stranded deoxyribonucleic acid unwinds and separates into single stranded strands through the breaking of hydrogen bonding between the bases. Both terms are used to refer… …

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  • 69DNA nanotechnology — seeks to make artificial, designed nanostructures out of nucleic acids, such as this DNA tetrahedron.[1] Each edge of the tetrahedron is a 20 base pair DNA double helix, and each vertex is a three arm junction. DNA n …

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  • 70The Centre for Applied Genomics — Infobox Company name = The Centre for Applied Genomics type = Genome Centre foundation = 1998 location city = Toronto location country = Canada location = locations = key people = [http://www.tcag.ca/scherer/ Dr. Stephen W. Scherer] , Scientific… …

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