microfilament
121dematin — Actin microfilament bundling protein (52 kD, but variants of similar molecular weight are reported) ; contains an SH3 domain and is extensively palmitoylated; associated with membrane of erythrocytes (protein 4.9) …
122focal adhesions — Areas of close apposition, and thus presumably anchorage points, of the plasma membrane of a fibroblast (for example) to the substratum over which it is moving. Usually 1 x 0.2 m m with the long axis parallel to the direction of movement; always… …
123hisactophilin — Actin binding protein (13.5 kD) from Dictyostelium discoideum. Promotes F actin polymerization and binds to microfilament bundles but is very pH sensitive as a result of having 31 histidine residues in a total of 118. Structure (though not… …
124ruffles — Projections at the leading edge of a crawling cell. In time lapse films the active edge appears to ‘ruffle’. The protrusions are apparently supported by a microfilament meshwork, and can move centripetally over the dorsal surface of a cell in… …
125severin — Calcium dependent F actin cleaving protein (40 kD) isolated from the slime mould Dictyostelium discoideum that binds irreversibly to the barbed ends of the microfilament; not, apparently, essential for movement …
126stereocilium — (= stereocilia (plural) ) Microfilament bundle supported projection, several microns long, from the apical surface of sensory epithelial cells (hair cells) in inner ear: like a microvillus, but larger. It is stiff and may act as a transducer… …
127vasodilator stimulated phosphoprotein — (= VASP) A 46/50 kD protein that is a substrate for both cAMP and cGMP dependent protein kinases and that is associated with microfilament bundles in many tissue cells. Abundant in platelets; phosphorylation of VASP will inhibit platelet… …
128microfilamentous — See microfilament. * * * …
