metabolic burst
1metabolic burst — (= respiratory burst) Response of phagocytes to particles (particularly if opsonized), and to agonists such as formyl peptides and phorbol esters; an enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen… …
2metabolic burst — respiratory b …
3burst — A sudden increase in activity. respiratory b. the marked increase in metabolic activity that occurs in phagocytes and certain other cells following binding of particles resulting in an increase in oxygen consumption, formation of su …
4respiratory burst — See metabolic burst …
5respiratory burst — The respiratory burst occurs when an activated phagocytic cell increases its oxygen consumption to support the increased metabolic activity of phagocytosis. The burst generates highly toxic oxygen products such as singlet oxygen, superoxide… …
6respiratory burst — a sequence of four metabolic events that occur during oxidative killing of ingested microorganisms by granulocytes and mononuclear phagocytes, consisting of (1) an increase in oxygen consumption, (2) formation of superoxide anion, (3) formation… …
7antioxidant — Any substance that inhibits oxidation usually because it is preferentially oxidised itself. Common examples are vitamin E ( a tocopherol) and vitamin C. Important for trapping free radicals generated during the metabolic burst and possibly for… …
8lucigenin — Compound used as a bystander substrate in assaying the metabolic burst of leucocytes by chemiluminescence. When oxidized by superoxide it emits light …
9luminol — Compound used as a bystander substrate in assaying the metabolic burst of leucocytes by chemiluminescence. When oxidized by the myeloperoxidase/hydrogen peroxide system, it emits light …
10myeloperoxidase — A metallo enzyme containing iron, found in the lysosomal granules of myeloid cells, particularly macrophages and neutrophils; responsible for generating potent bacteriocidal activity by the hydrolysis of hydrogen peroxide (produced in the… …
