conformational analysis
91X-ray crystallography — can locate every atom in a zeolite, an aluminosilicate with many important applications, such as water purification. X ray crystallography is a method of determining the arrangement of atoms within a crystal, in which a beam of X rays strikes a… …
92Protein — Proteins are large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid residues. The sequence of amino acids in a protein is defined by …
93Bcr-Abl tyrosine-kinase inhibitor — Bcr Abl tyrosine kinase inhibitors (TKI) are the first line therapy for most patients with chronic myelogenous leukemia (CML). In more than 90% cases CML is caused by chromosomal abnormality resulting in the formation of a so called Philadelphia… …
94Biological small-angle scattering — Small angle scattering is a fundamental method for structure analysis of materials, including biological materials. Small angle scattering allows one to study the structure of a variety of objects such as solutions of biological macromolecules,… …
95G protein-coupled receptor — G protein coupled receptors (GPCRs), also known as seven transmembrane domain receptors, 7TM receptors, heptahelical receptors, and G protein linked receptors (GPLR), comprise a large protein family of transmembrane receptors that sense molecules …
96Hemoglobin — Hemoglobin, human, adult (heterotetramer, (αβ)2) Structure of human hemoglobin. The protein s α and β subunits are in red and blue, and the iron containing heme groups in green. Fro …
97Heparin — Systematic (IUPAC) name see Hep …
98STX1A — Syntaxin 1A (brain) PDB rendering based on 1br0 …
99Conformation activity relationship — is the relationship between the biological activity and the conformation or conformational changes of a biomolecule. This terminology emphasizes the importance of dynamic conformational changes for the biological function, rather than the… …
100Discovery and development of HIV-protease inhibitors — Many major physiological processes depend on regulation of proteolytic enzyme activity and there can be dramatic consequences when equilibrium between an enzyme and its substrates is disturbed. In this prospective, the discovery of small molecule …
