chromosomal instability
1Microsatellite instability — Microsatellites are repeated sequences of DNA. Although the length of these microsatellites is highly variable from person to person, each individual has microsatellites of a set length. These repeated sequences are common, and normal. The most… …
2Chromosome instability syndrome — Chromosome instability syndromes are a group of inherited conditions associated with chromosomal instability and breakage. They often lead to an increased tendency to develop certain types of malignancies.[1] The following chromosome instability… …
3syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… …
4Caretaker gene — Changes in the genome that allow uncontrolled cell proliferation or cell immortality are responsible for cancer. It is believed that the major changes in the genome that lead to cancer arise from mutations in Tumor Suppressor Genes 1. In 1997,… …
5Deleted in Colorectal Cancer — Deleted in colorectal carcinoma Rendering based on PDB 2ED7 …
6Chromatin bridge — Classification and external resources DAPI staining allows for visualization of deoxyribonucleic acid portions of the two daughter cells. The thin “string like” DNA connecting them is defined as a chromatin bridge. Chromatin bridge is a mitotic… …
7Mutagen — In genetics, a mutagen (Latin, literally origin of change) is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level. As many… …
8Nijmegen-Breakage-Syndrom — Das Nijmegen Breakage Syndrom (Abkürzung: NBS; englisch: Nijmegen breakage syndrome) ist eine syndromale, seltene, angeborene Krankheit des Menschen mit einer Störung des Reparaturmechanismus der Erbsubstanz (DNA) in allen Zellen und Organen mit… …
9Chromosome — For a non technical introduction to the topic, see Introduction to genetics. Diagram of a replicated and condensed metaphase eukaryotic chromosome. (1) Chromatid – one of the two identical parts of the chromosome after S phase. (2)… …
10Centrosome — Schematic of typical animal cell, showing subcellular components. Organelles: (1) Nucleolus (2) Nucleus (3) Ribosomes (little dots) (4) Vesicle (5) Rough endoplasmic reticulum (ER) (6) Golgi apparatus (7) Cytoskeleton (8) Smooth ER (9)… …
