binding ring
51Drug — /droog/, n. Zoroastrianism. the cosmic principle of disorder and falsehood. Cf. Asha. [ < Avestan drauga] * * * I Any chemical agent that affects the function of living things. Some, including antibiotics, stimulants, tranquilizers,… …
52Development of dipeptidyl peptidase-4 inhibitors — Dipeptidyl peptidase 4 inhibitors (DPP 4 inhibitors) are enzyme inhibitors that inhibit the enzyme dipeptidyl peptidase 4 (DPP 4) and are a potent treatment for type 2 diabetes. Inhibition of the DPP 4 enzyme prolongs and enhances the activity of …
53Cannabinoid receptor antagonist — The discovery of the endogenous cannabinoid system led to the development of CB1 receptor antagonists. The first cannabinoid receptor antagonist, rimonabant, was described in 1994. Rimonabant blocks the CB1 receptor selectively and it has been… …
54Neuromuscular-blocking drug — Global view of a neuromuscular junction: 1. Axon 2. Motor end plate 3. Muscle fiber 4. Myofibril …
55(+)-CPCA — Systematic (IUPAC) name methyl (3R,4S) 4 (4 chlorophenyl) 1 methylpiperidine 3 carboxylate Clinical data Pregnancy cat …
56Discovery and development of triptans — Triptans is a word commonly used for a class of anti migraine drugs that are selective 5 hydroxytryptamine/serotonin1B/1D (5 HT1B/1D) agonists.[1] Migraine is a complex disease which affects about 15% of the population and can be highly disabling …
57Discovery and development of integrase inhibitors — The first human immunodeficiency virus (HIV) case was reported in the 1980s. Many drugs have been discovered to treat the disease but mutations in the virus and resistance to the drugs make development difficult. Integrase is a viral enzyme that… …
58Cohesin — This article is about the protein complex. For the protein domain in cellulose degrading bacteria, see Cohesin domain. Sister chromatid cohesion protein 1 Cohesin complex composed of SCC1 and SMC1 proteins.[1] …
59Life Sciences — ▪ 2009 Introduction Zoology In 2008 several zoological studies provided new insights into how species life history traits (such as the timing of reproduction or the length of life of adult individuals) are derived in part as responses to… …
60Quaternary ammonium muscle relaxants — are quaternary ammonium salts used as drugs for muscle relaxation, most commonly in anasthesia. It is necessary to prevent spontaneous movement of muscle during surgical operations. Muscle relaxants inhibit neuron transmission to muscle by… …
