antibody constant region
11variable region — n the part of the polypeptide chain of a light or heavy chain of an antibody that ends in a free amino group NH2, that varies greatly in its sequence of amino acid residues from one antibody to another, and that prob. determines the conformation… …
12Complementarity determining region — The upper part (Fab region) of an antibody. The complementarity determining regions of the heavy chain are shown in red (PDB 1IGT). Complementarity determining regions (CDRs) are regions within antibodies (also known as immunoglobulins) or T cell …
13V region — variable region the N terminal portion, composing one homology region, of an immunoglobulin heavy chain (VH) or light chain (VL); it varies in amino acid sequence among chains of a single type. The antigen binding sites of immunoglobulin… …
14Immunofluorescence — is the labeling of antibodies or antigens with fluorescent dyes. This technique is often used to visualize the subcellular distribution of biomolecules of interest. Immunofluorescent labelled tissue sections or cultures are studied using a… …
15immune system — Anat. a diffuse, complex network of interacting cells, cell products, and cell forming tissues that protects the body from pathogens and other foreign substances, destroys infected and malignant cells, and removes cellular debris: the system… …
16Immunoglobulin class switching — Mechanism of class switch recombination that allows isotype switching in activated B cells Immunoglobulin class switching (or isotype switching or isotypic commutation or class switch recombination(CSR)) is a biological mechanism that changes a B …
17Immunoglobulin — A protein produced by plasma cells and lymphocytes. Immunoglobulins are an essential part of the body s immune system which attach to foreign substances, such as bacteria, and assist in destroying them. Abbreviated Ig. The classes of… …
18Heavy chain — A heavy chain is the large polypeptide subunit of a protein complex, such as a motor protein (e.g. myosin, kinesin, or dynein) or antibody (or immunoglobulin). A typical antibody is composed of two immunoglobulin (Ig) heavy chains and two Ig… …
19IGKC — Immunoglobulin kappa constant, also known as IGKC, is a human gene that encodes a the constant domain of kappa type light chains for antibodies.cite web | title = Entrez Gene: IGKC immunoglobulin kappa constant| url =… …
20Nomenclature of monoclonal antibodies — List of stems for monoclonal antibody nomenclature[1][2][3] …
