Immunoglobulin heavy chain

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• Heavy chain — A heavy chain is the large polypeptide subunit of a protein complex, such as a motor protein (e.g. myosin, kinesin, or dynein) or antibody (or immunoglobulin). A typical antibody is composed of two immunoglobulin (Ig) heavy chains and two Ig… …   Wikipedia

• Heavy chain disease — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 442 DiseasesDB mult = DiseasesDB2|32226 | ICD10 = ICD10|C|88|1|c|81 ICD10|C|88|2|c|81 ICD9 = ICD9|273.2 ICDO = OMIM = MedlinePlus = eMedicineSubj = med eMedicineTopic = 958 eMedicine mult =… …   Wikipedia

• heavy chain — In general, the larger polypeptide in a multimeric protein. Thus the immunoglobulin heavy chain is of 50 kD, the light chain of 22 kD, whereas in myosin the heavy chain is very much larger (220 kD) than the light chains (heavy chain20 kD) …   Dictionary of molecular biology

• Immunoglobulin light chain — Schematic diagram of an typical antibody showing two Ig heavy chains (blue) linked by disulfide bonds to two Ig light chains (green). The constant (C) and variable (V) domains are shown …   Wikipedia

• heavy chain diseases — a group of rare malignant neoplasms of lymphoplasmacytic cells that secrete an M component consisting of monoclonal immunoglobulin heavy chains or heavy chain fragments; they are classified according to heavy chain type. See also alpha chain d.,… …   Medical dictionary

• Immunoglobulin class switching — Mechanism of class switch recombination that allows isotype switching in activated B cells Immunoglobulin class switching (or isotype switching or isotypic commutation or class switch recombination(CSR)) is a biological mechanism that changes a B …   Wikipedia

• Immunoglobulin A — (IgA) is an antibody playing a critical role in mucosal immunity. More IgA is produced in mucosal linings than all other types of antibody combined. [cite journal |author=S Fagarasan and T Honjo |title=Intestinal IgA Synthesis: Regulation of… …   Wikipedia

• Immunoglobulin M — Immunoglobulin M, or IgM for short, is a basic antibody that is present on B cells. It is the primary antibody against A and B antigens on red blood cells. IgM is by far the physically largest antibody in the human circulatory system. tructure… …   Wikipedia

• Immunoglobulin G — (IgG) is a monomeric immunoglobulin, built of two heavy chains γ and two light chains. Each IgG has two antigen binding sites. It is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids,… …   Wikipedia

• Immunoglobulin D — (IgD) is an antibody isotype that makes up about 1% of proteins in the plasma membranes of immature B lymphocytes where it is usually coexpressed with another cell surface antibody called IgM. IgD is also produced in a secreted form that is found …   Wikipedia