- reading frame mutation
- reading frame mutation.(Источник: «Англо-русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд-во ВНИРО, 1995 г.)
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Reading frame — In biology, a reading frame is a contiguous and non overlapping set of three nucleotide codons in DNA or RNA. There are 3 possible reading frames in a mRNA strand and six in a double stranded DNA molecule due to the two strands from which… … Wikipedia
Reading frame — One of the three possible ways to read a nucleotide sequence in DNA (depending upon whether reading starts with the first, second or third base in a triplet). * * * The grouping of nucleotides by threes into codons. See frame shift mutation.… … Medical dictionary
Open reading frame — In molecular genetics, an open reading frame (ORF) is a DNA sequence that does not contain a stop codon in a given reading frame[1]. Normally, inserts which interrupt the reading frame of a subsequent region after the start codon, cause… … Wikipedia
Mutation — A permanent change, a structural alteration, in the DNA or RNA. In humans and many other organisms, mutations occur in DNA. However, in retroviruses like HIV, mutations occur in RNA which is the genetic material of retroviruses. In most cases,… … Medical dictionary
Mutation — For other uses, see Mutation (disambiguation). Part of the Biology series on Evolution … Wikipedia
frame-shift mutation — Insertion or deletion of a number of bases not divisible by three in an open reading frame in a DNA sequence. Such mutations usually result in the generation, downstream, of nonsense, chain termination codons … Dictionary of molecular biology
Frameshift mutation — A frameshift mutation (also called a framing error) is a genetic mutation caused by indels, ie. insertion or deletion of a number of nucleotides that is not evenly divisible by three from a DNA sequence. Due to the triplet nature of gene… … Wikipedia
frameshift mutation — a mutation resulting from an insertion or deletion in a coding sequence that is not an exact multiple of 3 base pairs, so that from the point of mutation onwards, the codons are read out of phase; the reading frame of the gene is changed, and a… … Medical dictionary
frameshift mutation — A mutation that changes the reading frame of a DNA, either by the insertion or the deletion of nucleotides. Because of the triplet nature of codons, this occurs if the number of nucleotides involved is not a multiple of three … Glossary of Biotechnology
Melanoma — Classification and external resources A melanoma ICD 10 C43 … Wikipedia