conformational change

  • 41Discovery and development of tubulin inhibitors — Tubulin inhibitors interfere directly with the tubulin system which is in contrast to those drugs acting on DNA for cancer chemotherapy. Microtubules play an important role in eukaryotic cells. Alpha and beta tubulin, the main components of… …

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  • 42Insulin — This article is about the insulin protein. For uses of insulin in treating diabetes, see insulin therapy. Not to be confused with inulin. Insulin Computer generated image of six insulin molecules assembled in a hexamer, highlighting the threefold …

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  • 43Curtin–Hammett principle — The Curtin–Hammett principle is a principle in chemical kinetics proposed by David Yarrow Curtin and Louis Plack Hammett. It states that, for a reaction that has a pair of reactive intermediates or reactants that interconvert rapidly (as is… …

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  • 44Janus kinase — (JAK) is a family of intracellular non receptor tyrosine kinases that transduce cytokine mediated signals via the JAK STAT pathway. They were initially named just another kinase 1 2 (since they were just two of a large number of discoveries in a… …

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  • 45Heparin — Systematic (IUPAC) name see Hep …

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  • 46COPII — For the 1996 United Nations Climate Change Conference in Geneva, Switzerland‎, see COP 2 (climate conference). Sec23 homolog A Ribbon diagram of the crystallographic structure of the COPII heterodimer of Sec23 and Sec24. Alpha helices are in red… …

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  • 47Nicotinic acetylcholine receptor — Acetylcholine Nicotine …

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  • 48AAA proteins — Pfam box Symbol = AAA Name = ATPases associated with diverse cellular activities (AAA) width = caption = Pfam= PF00004 InterPro= IPR003959 SMART= PROSITE= PDOC00572 SCOP = 1nsf TCDB = OPM family= OPM protein= PDB=PDB3|1jbkA:201 286 PDB3|1qvrC:193 …

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  • 49Neuropharmacology — For the journal, see Neuropharmacology (journal). Neuropharmacology is the study of how drugs affect cellular function in the nervous system. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology …

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  • 50Ligand (biochemistry) — Myoglobin (blue) with its ligand heme (orange) bound. Based on PDB 1MBO For other uses of Ligand , see Ligand (disambiguation). In biochemistry and pharmacology, a ligand (from the …

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