Ariboflavinosis

Ariboflavinosis

Ariboflavinosis is the medical condition caused by deficiency of riboflavin (vitamin B2). Ariboflavinosis is most often seen in association with protein-energy malnutrition, and also in cases of alcoholism.

It was originally known as "pellagra sin pellagra", as it exhibits certain similarities to the niacin deficiency pellagra. The most common cause of riboflavin deficiency is an inadequate diet; thus, it occurs most frequently in populations consuming limited quantities of riboflavin-containing foods such as meats, eggs, milk, cheese, yogurt, leafy green vegetables and whole grains. Riboflavin deficiency can also occur in those with impaired liver function, which prevents proper utilization of the vitamin. Borderline riboflavin deficiency as a consequence of certain anti-retroviral medications has also been known to cause acute lactic acidosis.

The signs and symptoms of riboflavin deficiency typically include sore throat with redness and swelling of the mouth and throat mucosa, cheilosis and angular stomatitis (cracking of the lips and corners of the mouth), glossitis (magenta tongue with atrophy), seborrheic dermatitis or pseudo-syphilis (moist, scaly skin particularly affecting the scrotum or labia majora and the nasolabial folds), and a decreased red blood cell count with normal cell size and hemoglobin content (normochromic normocytic anemia).

Riboflavin deficiency is usually found together with other nutrient deficiencies, particularly of the other water-soluble vitamins. Phototherapy to treat jaundice in infants can cause increased degradation of riboflavin, leading to deficiency if not monitored closely. Persons with chronic alcoholism can have impaired absorption of riboflavin and other vitamins such as thiamine (see Wernicke's encephalopathy).

Studies of the Turkoman people of Iran, who have a significantly increased incidence of esophageal cancer, have shown some relationship between chronic riboflavin deficiency and the onset of esophageal malignancies. One study of pregnant women has found that riboflavin-deficient women were 4.7 times more likely to develop preeclampsia, though the mechanism for this is not known.

The US Recommended Daily Allowance (RDA) for riboflavin ranges from 1.1 to 1.3 milligrams per day for healthy adults to as high as 1.6 mg/day for pregnant or nursing women.

External links

* [http://lpi.oregonstate.edu/infocenter/vitamins/riboflavin/ Riboflavin] at the Linus Pauling Institute

References

*


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • ariboflavinosis — [ā rī΄bō flā΄və nō′sis] n. 〚 A 2 + RIBOFLAVIN + OSIS〛 a disorder resulting from a lack of riboflavin, characterized by cracking of the corners of the mouth and disturbances of vision * * * a·ri·bo·fla·vi·no·sis (ā rī …   Universalium

  • ariboflavinosis — [ā rī΄bō flā΄və nō′sis] n. [ A 2 + RIBOFLAVIN + OSIS] a disorder resulting from a lack of riboflavin, characterized by cracking of the corners of the mouth and disturbances of vision …   English World dictionary

  • ariboflavinosis — noun Etymology: New Latin Date: 1939 a deficiency disease due to inadequate intake of riboflavin and characterized by sores on the mouth …   New Collegiate Dictionary

  • ariboflavinosis — Properly hyporiboflavinosis : a nutritional condition produced by a deficiency of riboflavin in the diet, characterized by cheilosis and magenta tongue and usually associated with other manifestations of B vitamin deficiency. * * *… …   Medical dictionary

  • ariboflavinosis — ari·bo·fla·vin·o·sis …   English syllables

  • ariboflavinosis — n. the group of symptoms caused by deficiency of riboflavin (vitamin B2). These symptoms include inflammation of the tongue and lips and sores in the corners of the mouth …   The new mediacal dictionary

  • ariboflavinosis — …   Useful english dictionary

  • Арибофлавиноз (Ariboflavinosis) — ряд симптомов, возникающих при дефиците рибофлавина (витамина В2) в организме человека. К ним относятся: воспаление языка и губ, а также болезненные изъязвления в углах рта. Источник: Медицинский словарь …   Медицинские термины

  • арибофлавиноз — (ariboflavinosis; а + рибофлавин + оз) болезнь, развивающаяся вследствие отсутствия или недостатка в пище рибофлавина, а также при недостаточном его всасывании или усвоении; проявляется ангулярным стоматитом, хейлитом, глосситом, позже… …   Большой медицинский словарь

  • АРИБОФЛАВИНОЗ — (ariboflavinosis) ряд симптомов, возникающих при дефиците рибофлавина (витамина В2) в организме человека. К ним относятся: воспаление языка и губ, а также болезненные изъязвления в углах рта …   Толковый словарь по медицине

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”